What is Roxithromycin?

Roxithromycin Generic of Rulide


Roxithromycin acts by inhibiting bacterial protein synthesis. Roxithromycin combines with 50S ribosome subunits and interferes with the translocation process. Rulide inhibits the movement of new peptide to peptidyl site and thus ribosome fails to move along the messenger RNA. Thus peptide chain formation gets terminated and protein synthesis is suppressed. This mechanism of action prevents the further multiplication of bacterial cells.


Side effects of Roxithromycin / Generic Rulide

The common side effects reported with Roxithromycin are nausea, vomiting, diarrhea, epigastric pain, flatulence, head ache, dizziness, malaise, moniliasis or candidiasis, urticaria, rash, pruritis, angioedema and increase in serum transaminase levels. The increase in serum transaminase levels is seen especially in elderly patients.

Guidelines before using Roxithromycin / Generic Rulide

The Roxithromycin treatment can cause hepatic dysfunction. It is recommended that the total daily dosage be reduced in patients with hepatic or renal insufficiency. The prolonged use of Rulide can result in the growth of non-susceptible organisms like fungi It is not advisable to consume Roxithromycin during pregnancy and lactation. Rulide is contraindicated along with ergotamine compounds. Caution has to be exercised when Rulide is co-administered with drugs such as terfenadine, cisapride, disopyramide, warfarin, digoxin, theophylline, midazolam and cyclosporine.

What are the common dosages of Roxithromycin / Generic Rulide?

The recommended dosage of Rulide is 300mg once daily or 150mg twice daily. The recommended dosage for pediatric patients is 5-8mg/kg/day administered twice daily as divided doses.

Difference between Brand and Generic

Brand and generic Rulide contains Roxithromycin as the active ingredient and hence the effective is the same. The difference between brand and generic forms are packaging, pricing and the brand name. The mechanism of action is same for both generic and brand forms. You can buy cheap Rulide pills when it is sold as a generic variant.

Where and How to buy Roxithromycin / Generic Rulide

You can purchase Rulide medicine online from our pharmacy. When order Rulide drug online from us, it will reach your doorstep without any hassles. You can also save more when you buy Rulide online in more numbers with the volume discounts we offer.

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